show Abstracthide AbstractThe Chinese alligator, a freshwater crocodilian endemic to China, goes into hibernation in refuges during winter to save energy and survive the harshness of winter. In this study, we sequenced methylome of Chinese alligator of multiple tissues using bisulfte sequencing to comprehensively explore the epigenetic mechanism underlying hibernation and provide new insights into the conservation of Chinses alligator which are being threatened by climate change.